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The future elder was born on [[December 13]], 1889 to Emmanuel and Irene Makris and named Athanasios. He was born into a large family of simple, country folk. Even as an infant, Athanasios was devout, even observing the fasting rules regarding milk products while still an infant. When Athanasios was five, he convinced his newly-engaged godmother to spend the rest of her days in virginity. Athanasios, having preserved himself from worldly temptations, decided to enter a [[monastery]] at the age of seventeen. He asked his parents' blessing, which they were happy to give.

In March, 1906, he entered the [[Monastery of St. John the Theologian (Patmos, Greece)|Monastery of St. John the Theologian]], Patmos; in August, having earnt earned the love of the aging brotherhood, he was made a [[rassophore ]] and given the name Amphilochios. To fight the passions and temptations, Fr Amphilochios would employ strict fasting - ten mouthfuls of food at each meal on standard days, with seven or eight olives on fast days.

In 1911, the [[abbot]] of the Monastery of St. John the Theologian sent Fr Amphilochios to [[Mount Athos]] in order to learn wood-carving; in March 1913, he was tonsured to the Great Schema by Elder Antoniadis. Two months later, the abbot had the agreement of the brethren of the monastery to ordain Fr Amphilochios; but, because of a self-perception of inadequacy, he asked his travelling traveling companion (and ordinand) to continue while Fr Amphilochios went to Egypt and the Holy Lands. Fr Amphilochios asked the Patriarch of Jerusalem to receive him as one of the caretakers of the [[Church of the Holy Sepulchre(Jerusalem)|Holy Sepulchre]]. While the Patriarch was willing to do this, the Monastery insisted that he return, where they "punished" him by sending him to the hermitage of Apollo, alongside Elder Makarios, which made Fr Amphilochios very happy as he was better able to pray.

However, in 1919, Fr Amphilochios was [[ordination|ordained ]] to the [[diaconate ]] and, soon after, to the priesthood[[priest]]hood. He was assigned to the monastery's dependency on the island of Kos, also serving as confessor throughout the Dodecanese. In 1926, he was sent to the [[Cave of the Apocalypse]], Patmos. He spent much time with students of the Ecclesiastical Academy, which produced numerous elders and abbots.

In 1935, the occupying powers of the Dodecanese were the Italians, who influenced the Church by forcing a system of governance that made it easy to manipulate the Church. However, the Patriarch of Constantinople demanded that this situation be rectified for the new abbot. In response, the brotherhood elected Elder Amphilochios as abbot. Soon after, the seeds of the future female Monastery of the Annunciation began to be planted: the first building housed a training workshop for knitting and weaving, a guise under which to teach children Greek. In response, in 1937, the Italians exiled Elder Amphilochios to mainland Greece, where the Elder received hospitality from the [[Brotherhood of Theologians "Zoe"|Zoe brotherhood]] in Athens, from whence he travelled traveled throughout Greece; after which he travelled traveled to Crete, where he became spiritual father of the island.

His exile ended in 1939, and Elder Amphilochios returned to Patmos, being received with great joy. He did not, however, reassume his abbacy, but rather, focused on dependencies and the female Monastery of the Annunciation. The changeover of power in 1942, from the Italians to the Germans, did not greatly impact on the Elder's life. In 1947, Elder Amphilochios organised a small group of nuns [[nun]]s to assist the orphans of Rhodes (at that time, extremely poor) by establishing an orphanage, along with a unit for pregnant women.

At Easter, 1968, Elder Amphilochios received a forewarning of his coming repose, and was given two years to prepare himself and his children for his repose. Anxious for his spiritual children, he asked God with tears for more time to develop his children, after which the Mother of God and St. [[John the Theologian]] appeared to him and informed him that his request was denied. Soon after this, he received a bout of flu. Having made his final preparations, he reposed on [[April 16]], 1970.

* Gerontissa '''[[Gabrielia (Papayannis)]]''' - was tonsured [[tonsure]]d by him into the Great Schema by the elder on Patmos in the "Cave of St. Anthony", of the Monastery of the Evangelismos, just before she and the nun Tomasina left for India.