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Beuno was born in Powys, supposedly at Berriew, the grandson of a prince of that realm. After education and [[ordination]] in the [[monastery]] of Bangor-on-Dee in north-east Wales, he became an active [[missionary]], Cadfan, King of Gwynedd, being his generous benefactor… benefactor.

Cadwallon, Cadfan's son and successor, deceived Beuno about some land , and, when the saint demanding demanded justice, Cadwallon proved unsympathetic. Thereupon, Cadwallon's cousin Gwyddaint, in reparation, "gave to God and Beuno forever his township" of Clynnog Fawr, where the saint founded the famous [[abbey]].

Beuno became the guardian and restorer to life of his niece, the virgin Saint Winefride. He was relentless with hardened sinners, but full of compassion to those in distress. Before his death "on the seventh day of Easter" he had a wondrous vision.