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He criticized his contemporary prelates on the charge of Simony "epi simonia", and upheld the theory of the "Trisynthetou"(triple constitution of humanity)-i.e "Psyche"(Soul),"Pneuma"(Spirit),"Soma"(body).(''Tolika''). He is arguably one of the most important religious personalities of the 19th century, whose innovations turned the Holy Synod against him. He was condemned and jailed several times.(''Tolika''). He was a very prolific writer whose works were widely translated outside of Greece.
He arrived on the island of Zakynthos in July 1892, and again in August 1893, teaching out of exile (''L. Zoes''). A critic of Makrakis from Zakynthos was the primary school teacher Ioannis Siderokastritis, who wrote ''"O Anamorphotis Makrakes" (The Uneducated Makrakis)'' E.130--(Tharros, 98 -M.308).