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*318 Publication of ''[[On the Incarnation]]'' by [[Athanasius the Great]], influencing the condemnation of [[Arianism]]; beginnings of [[Arianism|Arian Controversy]].
*318 [[Pachomius the Great]], disciple of [[Anthony the Great]], organizes a community of ascetics at Tabennis in Egypt, founding [[cenobitic]] [[monasticism]].
*319 Translation of relics of [[Theodore the GeneralStratelates|Theodore Stratelates]] ("the General").
*320 Expulsion of [[Arius]] by [[Alexander of Alexandria]]; martyrdom of [[Forty Martyrs of Sebaste]].
*320-21 Licinius' measures against Christians in the east enforced.