On [[February 25]], 1962, Metropolitan Isaiah was [[ordination|ordained]] a [[deacon]] by His Eminence [[ArchbishopMetropolitan]] [[Iakovos '''Isaiah (CoucouzisChronopoulos) of America|Iakovos]] at Saint Spyridon Church in San Diego, California, having been Denver''' is the presiding [[tonsurehierarch]]d a [[monk]] on of the previous day. He received his ordination to the holy [[priest]]hood from His Grace Bishop Demetrios Metropolis of Olympos at Saint Sophia [[Cathedral]] in Los AngelesDenver, California, on a [[March 18diocese]], 1962. His first assignment in within the [[Greek Orthodox Archdiocese of America|Greek Orthodox Archdiocese]] was as assistant to the [[pastor]] at Holy Trinity Church in Salt Lake City, Utah. In December covering a twelve-state region (and parts of 1964 he was assigned as pastor at Saint John the Baptist Church two others) in Youngstown, Ohio. On [[November 30]], 1969, he was raised to the office of [[Archimandrite]] by Archbishop Iakovos at the [[consecration]] services Intermountain region of the new church and community center in YoungstownUnited States.

Archbishop Iakovos was reassigned the The Metropolitan is a native of New Hampshire, having been born in Portsmouth. He is one of four children born to Dennis and Mary (Kapsimalis) Chronopoulos who had immigrated to the United States from Olympia, Greece. After his primary and high school education, he served with distinction in the United States Marine Corps during the Korean conflict. In the autumn of 1954 he enrolled at [[Hellenic College Holy Cross Greek Orthodox School of Theology (Brookline, Massachusetts)|Hellenic CollegeHoly Cross Greek Orthodox Seminary]] and Holy Cross School of Theology as the Director of Student Life in August of 1971Brookline, Massachusetts. Taking a leave of absence from Upon his duties graduation in February 19751960, he enrolled as a undertook graduate student studies at the [[Theological School of Theology at the University of Thessaloniki, fulfilling requirements for the recognition of his master's degree in theology. He returned to the United States in July of that year and continued in his capacity as dean of studentsHalki]].

In September 1976 he On [[February 25]], 1962, Metropolitan Isaiah was given additional responsibilities [[ordination|ordained]] a [[deacon]] by His Eminence [[Archbishop]] [[Iakovos (Coucouzis) of America|Iakovos]] at Saint Spyridon Church in San Diego, California, having been [[tonsure]]d a [[monk]] on the college-seminary as previous day. He received his ordination to the Dean holy [[priest]]hood from Bishop [[Demetrios (Makris) of Administrative Affairs together with his position Olympos]] at Saint Sophia [[Cathedral]] in Los Angeles, California, on [[March 18]], 1962. His first assignment in the Archdiocese was as Dean of Studentsassistant to the [[pastor]] at Holy Trinity Church in Salt Lake City, Utah. In October 1977 December of 1964 he assumed additional duties was assigned as the Interim Pastor pastor at Saint Nicholas John the Baptist Church in PortsmouthYoungstown, New HampshireOhio. Relinquishing all of these positions in March 1979On [[November 30]], 1969, he was assigned as the Chancellor of raised to the Diocese office of Chicago under His Grace, [[BishopArchimandrite]] by Archbishop Iakovos at the [[Iakovos (Garmatis) of Chicago|Iakovosconsecration]] services of Chicagothe new church and community center in Youngstown.

Metropolitan Archbishop Iakovos next assigned Fr. Isaiah was elected to the rank of bishop by the [[Holy Synod]] of the [[Ecumenical Patriarch]]ate in Istanbul Hellenic College (ConstantinopleBrookline, Massachusetts), Turkey, on [[April 10|Hellenic College]], 1986. He was consecrated a bishop on [[May 25]], 1986, at and Holy Trinity Cathedral in New York City, and was given the title Cross School of ''Bishop of Aspendos'', a former Christian city in southwestern Asia Minor. In September 1986, His Eminence Archbishop Iakovos assigned him Theology as the Chancellor Director of the Archdiocese Student Life in New YorkAugust of 1971. Bishop Isaiah continued to function Taking a leave of absence from his duties in this capacity until [[June 23]], 1992February 1975, when he was elected Bishop enrolled as a graduate student at the School of Theology at the Diocese University of Denver by the Ecumenical PatriarchateThessaloniki, taking fulfilling requirements for the new title on [[June 24]], 1992, at special ceremonies recognition of his master's degree in the Archdiocesan Chapeltheology. He was enthroned as Bishop returned to the United States in July of Denver on [[September 10]], 1992, at that year and continued in the Greek Orthodox Cathedral capacity of the [[Assumption]] Dean of the [[Virgin Mary]] in Denver, ColoradoStudents.

In September 1976 he was appointed the Dean of Administrative Affairs, concurrent with his position as Dean of Students. In October 1977 he assumed additional duties as the interim pastor at Saint Nicholas Church in Portsmouth, New Hampshire. Relinquishing all of these positions in March 1979, he was assigned as the [[Chancellor]] of the Diocese of Chicago under His Grace, [[Bishop]] [[Iakovos (Garmatis) of Chicago|Iakovos]] of Chicago. Metropolitan Isaiah was elected to the episcopacy by the [[Holy Synod]] of the [[Ecumenical Patriarch]]ate in Istanbul (Constantinople), Turkey, on [[April 10]], 1986. He was consecrated a bishop on [[May 25]], 1986, at Holy Trinity Cathedral in New York City, and was given the title of ''Bishop of Aspendos'', a former Christian city in southwestern Asia Minor. In September 1986, Archbishop Iakovos assigned him as the Chancellor of the Archdiocese in New York. Bishop Isaiah continued to function in this capacity until [[June 23]], 1992, when he was elected Bishop of Denver by the Ecumenical Patriarchate, taking the new title on [[June 24]], 1992, at special ceremonies in the Archdiocesan Chapel of St. Paul. He was enthroned as Bishop of Denver on [[September 10]], 1992, at the Greek Orthodox Cathedral of the [[Assumption]] of the [[Virgin Mary]] in Denver, Colorado. On [[November 24]], 1997, the Holy and Sacred Synod of the Ecumenical Patriarchate elevated him as to Metropolitan of Proikonisos and Presiding [[Hierarch]] of the Greek Orthodox Diocese of Denver. Metropolitan Isaiah was also appointed as President of Hellenic College/Holy Cross Greek Orthodox School of Theology on [[July 1]], 1997, by His Eminence Archbishop [[Spyridon (Papageorge) of America|Spyridon]] of America. He accepted a one-year term which officially ended on [[August 14]], 1998.