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Where some patristic writers speak of NFP and withdrawal (''coitus interruptu''s), they condemn it (St. Augustine <ref>Saint, Bishop of Hippo Augustine (1887). "Chapter 18.—Of the Symbol of the Breast, and of the Shameful Mysteries of the Manichæans". In Philip Schaff. A Select Library of the Nicene and Post-Nicene Fathers of the Christian Church, Volume IV. Grand Rapids, MI: WM. B. Eerdmans Publishing Co.</ref>, St Jerome <ref>Jerome, Against Jovinian 1:20, (AD 393) http://www.newadvent.org/fathers/30091.htm</ref>, Clement of Alexandria)<ref>Clement of Alexandria, The Instructor of Children 2:10:91:2 (AD 191)</ref>. However, as John Noonan has shown, in each of these cases their position followed from their unbiblical idea, adopted from Stoic philosophy, that sexual desire was evil and thus marital intercourse was only permissible for procreation.<ref>Noonan, chapters III and IV.</ref>
While some of the Fathers' references to such chemical methods seem clearly to refer to their destroying a child that is being formed in the womb after the sexual act that gave rise to it (abortion), others seem to also include the idea that these methods were also used to "sterilise" the womb to prevent this process from being initiated (St John Chrysostom in his 24th Homily on Romans and St. Caeserius of Arles in his first Sermon)<ref>St John Chrysostom, Homilies on Romans 24 [A.D. 391]). http://www.newadvent.org/fathers/210224.htm</ref><ref>St Caeserius of Arles, (Sermons 1:12 [A.D. 522]). </ref>. We should also keep in mind that there was no single prevailing scientific model for how conception took place in the "Age of the Fathers". There were at least two scientific models of conception: the Hippocratic/Galenic "two semen" model (closer to our own), whereby both male and female contributed components to the child-in-formation, and also the Aristotelian "one semen model", in which the male semen was the only component of the early child-in-formation and was planted in the fertile soil of the womb during sex (the problem of when "human personhood" began was a separate issue). No Church Fathers weigh into these scientific debates. However, those that do mention chemical methods, condemn them, whether taken before sex to prevent pregnancy, or taken after sex to destroy the contents of the womb. Thus, all three available methods of preventing pregnancy (coitus interruptus, natural family planning, and herbal/chemical treatments) were condemned at some point by Church Fathers, and none were ever endorsed as acceptable.
Two dissenting positions are:
