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Ambrose was born a citizen of Rome in Trier, Germany, between 337 and 340. His family were Christians. His father was prefect of Gallia Narbonensis, his mother a woman of intellect. He was educated in Rome a for a career following that of his father. As his education in literature, law, and rhetoric progressed he was placed by praetor Anicius Probus on the council of Ligura and Emilia and then made consular prefect with headquarters in Milan. In this position he established himself as an excellent administrator.

 In the contention between the Nicene and Arian parties for the succession to the vacant [[see]] of Milan after the death of the Arian Auxentius in 374, an address that Ambrose delivered in the midst of the crisis led to his acclamation as the only competent candidate for the position of bishop of Milan. While he was only a catechumen, he was quickly baptized and then within days installed as the new bishop of Milan. He quickly began studying theological theology under Simplician, a [[presbyter]] of Rome. After settling his personal life, dividing his money among the poor and arranging for the care of his family, and he, then, devoted himself to the work of the church.