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He was born in Sinope of Pontus in 1897, where he began his primary education. He continued his studies at the [[Halki|Theological School of Halki]] under the protection of [[Metropolitan]] [[Germanos Karavaggelis]] of Amaseia. He was [[ordination|ordained]] into the [[diaconate]] in 1918 and appointed a teacher in the City School of Theira. He served as the [[Archdeacon]] of Metropolitans [[Gregorios of Chalcedon]] and [[Joachim of Ephesus]], before becoming a deacon in the [[Ecumenical Patriarchate]] in 1920. He then served in various positions on the Board of the Halki School, including secretary, codewriter, subsecretary, and archsecretary before being [[ordination|ordained]] a [[presbyter]] and [[archimandrite]] on [[January 1]], 1928. He later became Metropolitan of Philadelphia in February 1930 before ascending to the Patriarchal throne in 1946.
Officially he resigned in 1948 due to poor health. Unofficially, he was forced to resign by western powers who didn't approve of his close ties with the Patriarch of Moscow, as the Cold War was beginning to take shape.
He was succeeded by Archbishop [[Athenagoras I (Spyrou) of Constantinople|Athenagoras]] of the Greek Orthodox Archdiocese of America. He died in Switzerland on [[January 1]], 1972.